Bamocaftor

Bamocaftor

• Product Name Alternative: VX-659
• CAS Number: 2204245-48-5
• UNSPSC Description: Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore F508del-CFTR protein function. Bamocaftor can be used combine with Tezacaftor (HY-15448) and Ivacaftor (HY-13017) in cystic fibrosis research[1].
• Target Antigen: CFTR
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/bamocaftor.html
• Purity: 99.09
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=CC=C(N2N=C(OCCC3(C(F)(F)F)CC3)C=C2)N=C1N4C(C)(C)C[C@H](C)C4)NS(=O)(C5=CC=CC=C5)=O
• Molecular Weight: 591.64
• References & Citations: [1]Ghelani DP, et al. Emerging Cystic Fibrosis Transmembrane Conductance Regulator Modulators as New Drugs for Cystic Fibrosis: A Portrait of in Vitro Pharmacology and Clinical Translation.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Phase 2