Anti-Calbindin 1 (CALB1)(CALB1/2782)
CAT:
37-BNUB2782-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Calbindin 1 (CALB1)(CALB1/2782)
- Description: Calbindin 1, also known as calbindin D28K, is a member of a family of calcium binding proteins. This protein family also includes calmodulin, calbindin 2, S-100, and troponin C. Calbindin 1 is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, calbindin 1 acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, calbindin 1 modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, calbindin 1 has been implicated to play a role in apoptosis and microtubule function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: Calbindin; Calbindin 1; Calbindin D28; Calbindin D28K; CALB1; Vitamin D dependent calcium binding protein
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: CALB1
- Gene ID: 793
- NCBI Gene ID: 65425
- UniProt: P05937
- Cellular Locus: Nucleus & cytoplasm
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant fragment (around aa 7-96) of human CALB1 protein (exact sequence is proprietary)
- Target Antigen: Calbindin 1
- Clonality: Monoclonal
- Isotype: IgG2b κ
- Clone: CALB1/2782
- Conjugation: Purified, with BSA
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Field of Research: Ion channels
- Positive Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.
- Concentration: 0.2 mg/mL
- Buffer: PBS, 0.05% BSA, 0.05% azide
- Molecular Weight: 52 kDa
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years