Cefpodoxime Proxetil

Cefpodoxime Proxetil

• CAS Number: 87239-81-4
• UNSPSC Description: Cefpodoxime proxetil is an orally administered broad spectrum third-generation cephalosporin. Cefpodoxime proxetil has anti-bacterial activity. Cefpodoxime proxetil binds to penicillin binding proteins (PBPs) which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis[1][2].
• Target Antigen: Antibiotic; Bacterial; Penicillin-binding protein (PBP)
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/cefpodoxime-proxetil.html
• Purity: 98.15
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=C(C(N12)=C(COC)CS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)OC(OC(OC(C)C)=O)C
• Molecular Weight: 557.60
• References & Citations: [1]Iqbal S, et al. In vitro Spectroscopic studies on drug interaction of cefpodoxime proxetil and H2 receptor blockers. Pak J Pharm Sci. 2019 Mar;32(2 (Supplementary)):881-887.|[2]Pahwa R, Rana A S, Dhimans S, et al. Cefpodoxime proxetil: an update on analytical, clinical and pharmacological aspects [J]. J Curr Chem Pharm Sc, 2015, 5(2): 56-66.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched