Anti-BMI1 (Oncogene and Stem Cell Marker)(BMI1/2690), CF405S conjugate
CAT:
37-BNC042690-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-BMI1 (Oncogene and Stem Cell Marker)(BMI1/2690), CF405S conjugate
- Description: The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: BMI1; Polycomb complex protein BMI1; B lymphoma Mo MLV insertion region 1 homolog; BMI1 polycomb ring finger oncogene; Polycomb group ring finger 4; RING finger protein 51
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: BMI1
- Gene ID: 648
- NCBI Gene ID: 380403
- UniProt: P35226
- Cellular Locus: Cytoplasmic|Nucleus
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant fragment (around aa 142-326) of human BMI1 protein (exact sequence is proprietary)
- Target Antigen: BMI1
- Clonality: Monoclonal
- Isotype: IgG2a κ
- Clone: BMI1/2690
- Conjugation: CF405S
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Field of Research: Cancer, Developmental biology
- Positive Control: HeLa or Jurkat cells. Colon Carcinoma.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: ~41 kDa
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years