STAT2 (STAT2/2650), 1mg/mL

CAT: 0037-BNUM2650-50Size: 1x 50 µLDry Ice: NoHazardous: No
CAT#:0037-BNUM2650-50Size:1x 50 µL
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Description
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
Homo sapiens interferon alpha induced transcriptional activator; interferon alpha induced transcriptional activator (ISGF3) ; P113; signal transducer and activator of transcription 2 113kD (STAT113) ; Signal transducer and activator of transcription 2 (STAT2)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
STAT2
Gene ID
6773
NCBI Gene ID
530595
UniProt
P52630
Swiss Prot
P52630
Host
Mouse
Species Reactivity
Human
Reactivity
STAT2
Immunogen
Recombinant full-length human STAT2 protein
Target Antigen
STAT2
Clonality
Monoclonal
Clone
STAT2/2650
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
113 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free
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