Anti-Guanine nucleotide-binding protein alpha-q / GNAQ / G-ALPHA-q(GNAQ/2434), Biotin conjugate

• Description:

  GNAQis 359 amino acids long and is identical in all but 1 amino acid residue to the mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included several small deletions and insertions that altered the reading frame, multiple single based changes, and a premature termination codon in the open reading frame, all hallmarks of a processed pseudogene. Probes derived from human GNAQ cDNA sequence mapped both chromosomes 2 and 9 in higher constringency genomic blot analyses of DNA from a panel of human/rodent hybrid cell lines. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  CMC1; G alpha Q; G protein alpha Q; GAQ; guanine nucleotide binding protein (G protein); q polypeptide; Guanine nucleotide-binding protein G(q) subunit alpha; SWS

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  GNAQ

• Gene ID:

  2776

• NCBI Gene ID:

  269782

• UniProt:

  P50148

• Cellular Locus:

  Plasma membrane

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Recombinant full-length human GNAQ protein

• Target Antigen:

  G-Alpha-q | GNAQ | Guanine nucleotide-binding protein Alpha-q

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Clone:

  GNAQ/2434

• Conjugation:

  Biotin

• Source:

  Animal

• Positive Control:

  HL-60, MOLT-4 and MCF-7 cells. Predominantly expressed in ovary, prostate, testis and colon.

• Concentration:

  0.1 mg/mL

• Buffer:

  PBS, 0.1% BSA, 0.05% azide

• Molecular Weight:

  45 kDa

• Additionnal Information:

  For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4