Login

Anti-Cyclin A2 (S- & G2-phase Cyclin)(CCNA2/2333), CF647 conjugate

CAT:
37-BNC472333-100
Size:
100 µL
Price:
Ask
For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Anti-Cyclin A2 (S- & G2-phase Cyclin)(CCNA2/2333), CF647 conjugate - image 1
Anti-Cyclin A2 (S- & G2-phase Cyclin)(CCNA2/2333), CF647 conjugate - image 2
Thumbnail 1
Thumbnail 2

Anti-Cyclin A2 (S- & G2-phase Cyclin)(CCNA2/2333), CF647 conjugate

  • Description: Recognizes a protein of 54 kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Synonyms: CCN1; CCNA; CCNA2; Cyclin A2
  • CAS Number: 9007-83-4
  • UNSPSC: 41116161
  • UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
  • Gene Name: CCNA2
  • Gene ID: 890
  • NCBI Gene ID: 58974
  • UniProt: P20248
  • Cellular Locus: Nucleus & cytoplasm
  • Host: Mouse
  • Species Reactivity: Human
  • Immunogen: Full length recombinant Cyclin A2 protein
  • Target Antigen: Cyclin A2
  • Clonality: Monoclonal
  • Isotype: IgG2a κ
  • Clone: CCNA2/2333
  • Conjugation: CF647
  • Source: Animal
  • Applications: IHC, FFPE (verified)
  • Validated Applications: IHC, FFPE
  • Positive Control: K-562 and HeLa cells; Tonsil.
  • Concentration: 0.1 mg/mL
  • Buffer: PBS, 0.1% BSA, 0.05% azide
  • Molecular Weight: 54 kDa
  • Shipping Conditions: Room temperature
  • Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
  • Shelf Life: 2 years

Datasheet

MSDS