Anti-SOX9 / SRY-box 9(SOX9/2287R), Biotin conjugate

Anti-SOX9 / SRY-box 9(SOX9/2287R), Biotin conjugate

• Description: The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
• Synonyms: CMD 1; campomelic dysplasia autosomal sex reversal; SRA1; SRXX2; SRXY10; SRY (sex determining region Y) box 9; SRY related HMG box gene 9; Transcription factor SOX 9
• CAS Number: 9007-83-4
• UNSPSC: 41116161
• UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
• Gene Name: SOX9
• Gene ID: 6662
• NCBI Gene ID: 647409
• UniProt: P48436
• Cellular Locus: Nucleus
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant human full-length SOX9 protein
• Target Antigen: SOX9 | SRY-box 9
• Clonality: Recombinant Monoclonal
• Isotype: IgG
• Clone: SOX9/2287R
• Conjugation: Biotin
• Source: Animal
• Positive Control: Human Skin Hair follicles.
• Concentration: 0.1 mg/mL
• Buffer: PBS, 0.1% BSA, 0.05% azide
• Molecular Weight: 56 kDa
• Additionnal Information: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
• Shipping Conditions: Room temperature
• Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
• Shelf Life: 2 years