Cleaved-NOTCH1 (V1754) Antibody

CAT: 0399-CSB-PA000057-01Size: 50 µgDry Ice: NoHazardous: No

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CAT#:0399-CSB-PA000057-01Size:50 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Gene Aliases

HN1 antibody; Neurogenic locus Notch homolog protein 1 antibody; NICD antibody; NOTC1_HUMAN antibody; Notch 1 antibody; Notch 1 intracellular domain antibody; Notch homolog 1 translocation associated antibody; notch1 antibody; TAN1 antibody; Translocation associated Notch protein TAN1 antibody; Translocation-associated notch protein TAN-1 antibody

UniProt

P46531

Host

Rabbit

Antigen Species

Human

Reactivity

Human, Mouse, Rat

Target Antigen

Synthesized peptide derived from the Internal region of Human Notch 1.

Target

NOTCH1

Clonality

Polyclonal

Conjugation

Non-conjugated

Field of Research

Neuroscience

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Conditions

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Type

Polyclonal Antibody

Tested Applications

WB, IHC, ELISA; WB:1:500-1:2000, IHC:1:100-1:300, ELISA:1:20000

Isotype

IgG

UniProtKB · P46531

Neurogenic locus notch homolog protein 1

NOTC1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P46531
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: NOTCH1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Notch 1, hN1
EC number: —
Processing: Precursor
Secondary accessions: Q59ED8, Q5SXM3

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Biological process

AngiogenesisDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

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