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Phospho-ERBB2 (Y877) Antibody

CAT: 0013-GTR18328066-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18328066-01Size:50 µL
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Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL
UniProt
P04626
Reactivity
Human
Immunogen
This ERBB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y877 of human ERBB2.
Target
ERBB2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Dilution
WB - 1:1000, DB - 1:500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
137910 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Mouse, Rat
Tested Applications
DOT, WB
NCBI Accession Number
NP_004439.2, NP_001005862.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P04626

Receptor tyrosine-protein kinase erbB-2

ERBB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04626
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERBB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
B2RZG3, B4DHN3, Q14256, Q6LDV1, Q9UMK4, X5D2V5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorKinaseReceptorTransferaseTyrosine-protein kinase

Coding sequence diversity

Alternative initiationAlternative splicingChromosomal rearrangement

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCell projectionCytoplasmEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

Biological process

TranscriptionTranscription regulation

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