Anti-CD134, Mouse (OX40)(OX-86), CF640R conjugate
CAT:
37-BNC402004-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-CD134, Mouse (OX40)(OX-86), CF640R conjugate
- Description: CD134 is a type I integral membrane protein. This receptor is expressed on activated CD4 and CD8 T cells and B cells. The CD134 binds to CD134 ligand (CD252) to provide a costimulatory signal that is independent of CD28. CD134 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. CD134 is also involved in the stimulation of T cells, T dependent humoral response and generation of optimal CD4 T cell responses in vivo and in vitro. CD134 is expressed on activated CD4 T lymphocytes, and its ligand, CD134L, is found preferentially on activated B cells. Engagement of CD134 with its ligand, CD134L, delivers a strong costimulatory signal to effector T cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: CD134; IMD16; Lymphoid activation antigen (ACT35); OX40 cell surface antigen; OX40L receptor; TAX transcriptionally activated glycoprotein 1 receptor; Tumor necrosis factor receptor superfamily member 4 (TNFRSF4); Txgp1l
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene ID: 22163
- NCBI Gene ID: 13885
- UniProt: P47741
- Cellular Locus: Plasma membrane
- Host: Rat
- Species Reactivity: Mouse
- Immunogen: Purified recombinant Mouse OX-40 antigen
- Target Antigen: CD134,
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: OX-86
- Conjugation: CF640R
- Source: Animal
- Applications: Flow, surface (published) | Functional studies (published) | IF (published) | WB (published)
- Validated Applications: FC, IF, WB
- Positive Control: MPBMC's. Spleen, Thymus or Lymph Node.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: ~50 kDa
- References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2000) 164:2160-2169. (functional studies) Exp Med (2003) 198(5): 737-746. (Flow, surface) Am J Respir Crit Care Med (2010) 181: 688-698. (WB) J Leukoc Biol (2007) 81: 766-774. (IF)
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years