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XRCC6 Antibody (Center)

CAT: 0013-GTR18327783-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18327783-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1
UniProt
P12956
Reactivity
Human
Immunogen
This XRCC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human XRCC6. Antigen Region: 228-254 aa.
Target
XRCC6
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
IF - 1:10-50, WB - 1:1000, IHC-P - 1:50-100, FC - 1:10-50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
69843 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
FC, IF, IHC-P, WB
NCBI Accession Number
NP_001460.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P12956

DNA repair protein Ku70

XRCC6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12956
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
XRCC6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.2.99.18, 5.6.2.4
Processing
—
Secondary accessions
B1AHC8, Q6FG89, Q9UCQ2, Q9UCQ3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingHelicaseHydrolaseIsomeraseLyaseMultifunctional enzyme

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

ChromosomeCytoplasmNucleus

Biological process

DNA damageDNA recombinationDNA repairHost-virus interactionImmunityInnate immunityTranscriptionTranscription regulation

Disease

Systemic lupus erythematosus

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