Anti-Epstein-Barr Virus (LMP-1)(CS2), Biotin conjugate

Anti-Epstein-Barr Virus (LMP-1)(CS2), Biotin conjugate

• Description: This antibody is a mixture of four different monoclonal antibodies. This antibody is specific to 60 kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the EBV. Each clone reacts with different epitopes on the hydrophilic C-terminus of the cytoplasmic domain of LMP-1. This antibody stains strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. EBV, also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
• Synonyms: EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Human Herpesvirus 4 (HHV4)
• CAS Number: 9007-83-4
• UNSPSC: 41116161
• UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
• Gene Name: Not Applicable
• UniProt: Not Applicable
• Cellular Locus: Nucleus
• Host: Mouse
• Species Reactivity: EBV
• Immunogen: Recombinant fusion protein containing the sequence of bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP
• Target Antigen: Epstein-Barr Virus
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Clone: CS2
• Conjugation: Biotin
• Source: Animal
• Applications: IHC, FFPE (published) | IHC, frozen (published) | IP (published) | WB (published)
• Validated Applications: IHC, FFPE, IHC, IP, WB
• Positive Control: EBV-infected cells. Tissues.
• Concentration: 0.1 mg/mL
• Buffer: PBS, 0.1% BSA, 0.05% azide
• Molecular Weight: 60 kDa
• Additionnal Information: ELISA: For coating, purchase antibody without BSA; Western blot 1-2 ug/mL; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
• References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Exp Med (1993) 177: 339-349. (IHC, frozen; WB; mix of clones CS1-4) J Clin Pathol (1995) 48:438-442. (IHC, FFPE; mix of clones CS1-4) EMBO J (1999)18:3064-3073. (IP; mix of clones CS1-4)
• Shipping Conditions: Room temperature
• Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
• Shelf Life: 2 years