Anti-Epstein-Barr Virus (LMP-1)(CS1), Biotin conjugate

• Description:

  This antibody is a mixture of four different monoclonal antibodies. This antibody is specific to 60 kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the EBV. Each clone reacts with different epitopes on the hydrophilic C-terminus of the cytoplasmic domain of LMP-1. This antibody stains strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. EBV, also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Human Herpesvirus 4 (HHV4)

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  Not Applicable

• UniProt:

  Not Applicable

• Cellular Locus:

  Nucleus

• Host:

  Mouse

• Species Reactivity:

  EBV

• Immunogen:

  Recombinant fusion protein containing the sequence of bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP

• Target Antigen:

  Epstein-Barr Virus

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  CS1

• Conjugation:

  Biotin

• Source:

  Animal

• Applications:

  IHC, FFPE (published) | IHC, frozen (published) | IP (published) | WB (published)

• Validated Applications:

  IHC, FFPE, IHC, IP, WB

• Positive Control:

  EBV-infected cells. Tissues.

• Concentration:

  0.1 mg/mL

• Buffer:

  PBS, 0.1% BSA, 0.05% azide

• Molecular Weight:

  60 kDa

• Additionnal Information:

  ELISA: For coating, purchase antibody without BSA; Western blot 1-2 ug/mL; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

• References & Citations:

  Note: References for this clone sold by other suppliers may be listed for expected applications. J Exp Med (1993) 177: 339-349. (IHC, frozen; WB; mix of clones CS1-4) J Clin Pathol (1995) 48:438-442. (IHC, FFPE; mix of clones CS1-4) EMBO J (1999)18:3064-3073. (IP; mix of clones CS1-4)

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4