Anti-CD268 / BAFFR / TNFRSF13C(BAFFR/1557), CF488A conjugate
CAT:
37-BNC881557-500
Size:
500 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-CD268 / BAFFR / TNFRSF13C(BAFFR/1557), CF488A conjugate
- Description: Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) ; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: TNFRSF13C; BAFFR; BR3; BAFF receptor; BLyS receptor 3; CD268; CD268 antigen; CVID4; Prolixin; BAFF-R; BROMIX
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: TNFRSF13C
- Gene ID: 115650
- NCBI Gene ID: 344088
- UniProt: Q96RJ3
- Cellular Locus: Plasma membrane
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant full-length human CD268 protein
- Target Antigen: BAFFR | CD268 | TNFRSF13C
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: BAFFR/1557
- Conjugation: CF488A
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Positive Control: Raji cells. Tonsil and lymph node.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 19 kDa (Monomer); 40 kDa (Dimer)
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years