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Parkin Antibody (C-term)

CAT: 0013-GTR18327430Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18327430Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
E3 ubiquitin-protein ligase parkin, 632-, Parkinson juvenile disease protein 2, Parkinson disease protein 2, PARK2, PRKN
UniProt
O60260
Reactivity
Human, Mouse
Immunogen
This Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human Parkin. Antigen Region: 387-417 aa.
Target
PRKN (HGNC:8607)
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Metabolism Research, Neuroscience
Dilution
IF - 1:10-50, WB - 1:1000, IHC-P - 1:50-100, FC - 1:10-50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
51641 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
FC, IF, IHC-P, WB
NCBI Accession Number
NP_004553.2, NP_054642.2, NP_054643.2
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · O60260

E3 ubiquitin-protein ligase parkin

PRKN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60260
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRKN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Parkin
EC number
2.3.2.31
Processing
—
Secondary accessions
A3FG77, A8K975, D3JZW7, D3K2X0, Q5TFV8, Q5VVX4, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AutophagyTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

Cell projectionCytoplasmEndoplasmic reticulumMembraneMitochondrionMitochondrion outer membraneNucleusSynapse

Disease

Disease variantNeurodegenerationParkinson diseaseParkinsonism

PTM

Isopeptide bondPhosphoproteinS-nitrosylationUbl conjugation

Ligand

Metal-bindingZinc

Domain

RepeatZinc-finger

Molecular function

Transferase

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