Anti-ALDH1A1 (Aldehyde Dehydrogenase 1A1)(ALDH1A1/1382)

Anti-ALDH1A1 (Aldehyde Dehydrogenase 1A1)(ALDH1A1/1382)

• Description: Aldehyde dehydrogenase 1 family member A1 (ALDH1A1), also known as retinal dehydrogenase 1, belongs to the aldehyde dehydrogenase enzyme family, which is involved in the metabolism of alcohol. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
• Synonyms: Aldehyde dehydrogenase family 1 member A1; ALDH1A1; Retinal dehydrogenase 1; Retinaldehyde Dehydrogenase 1; Epididymis Luminal Protein
• CAS Number: 9007-83-4
• UNSPSC: 41116161
• UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
• Gene Name: ALDH1A1
• Gene ID: 216
• NCBI Gene ID: 76392
• UniProt: P00352
• Cellular Locus: Cytoplasmic
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Purified recombinant fragment of human ALDH1A1 (aa 315-434), expressed in HK293 Cells.
• Target Antigen: Aldehyde dehydrogenase 1
• Clonality: Monoclonal
• Isotype: IgG
• Clone: ALDH1A1/1382
• Conjugation: Purified, with BSA
• Source: Animal
• Positive Control: HepG2 or A549 cells. Colon or Testicular Carcinoma.
• Concentration: 0.2 mg/mL
• Buffer: PBS, 0.05% BSA, 0.05% azide
• Molecular Weight: 56 kDa
• Additionnal Information: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
• References & Citations: Xu J, Muller S, et al. Eur J Cancer. 2012 Jul;48(11):1682-91
• Shipping Conditions: Room temperature
• Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
• Shelf Life: 2 years