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PERK (EIF2AK3) Antibody (Center)

CAT: 0013-GTR18326611-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18326611-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Eukaryotic translation initiation factor 2-alpha kinase 3, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK, EIF2AK3, PEK, PERK
UniProt
Q9NZJ5
Reactivity
Human
Immunogen
This PERK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human EIF2AK3.
Target
EIF2AK3 {ECO:0000303|PubMed:10932183, ECO:0000312|HGNC:HGNC:3255}
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Dilution
WB - 1:1000, IHC-P - 1:10-50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
125216 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Mouse, Rat
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_004827.4
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q9NZJ5

Eukaryotic translation initiation factor 2-alpha kinase 3

E2AK3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NZJ5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EIF2AK3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
Precursor
Secondary accessions
A0AVH1, A0AVH2, B2RCU9, O95846, Q53QY0, Q53SB1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

ADP-ribosylationGlycoproteinPhosphoprotein

Ligand

ATP-bindingNucleotide-binding

Disease

Diabetes mellitusDisease variant

Cellular component

Endoplasmic reticulumMembrane

Molecular function

KinaseSerine/threonine-protein kinaseTransferaseTyrosine-protein kinase

Domain

SignalTransmembraneTransmembrane helix

Biological process

Stress responseTranslation regulationUnfolded protein response

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