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NLRP3 Antibody (N-term)

CAT: 0013-GTR18327113-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18327113-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
NACHT, LRR and PYD domains-containing protein 3, Angiotensin/vasopressin receptor AII/AVP-like, Caterpiller protein 11, CLR11, Cold autoinflammatory syndrome 1 protein, Cryopyrin, PYRIN-containing APAF1-like protein 1, NLRP3, C1orf7, CIAS1, NALP3, PYPAF1
UniProt
Q96P20
Reactivity
Human
Immunogen
This NLRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-91 amino acids from the N-terminal region of human NLRP3. Antigen Region: 65-91 aa.
Target
NLRP3 {ECO:0000303|PubMed:17907925, ECO:0000312|HGNC:HGNC:16400}
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Dilution
WB - 1:1000-1:2000, IHC-P - 1:10-50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
118173 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_001230062.1, NP_004886.3, NP_001120933.1, NP_001073289.1, NP_899632.1, NP_001120934.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q96P20

NACHT, LRR and PYD domains-containing protein 3

NLRP3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96P20
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NLRP3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.-
Processing
—
Secondary accessions
A0A024R5Q0, B2RC97, B7ZKS9, B7ZKT2, B7ZKT3, O75434, Q17RS2, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorHydrolase

PTM

ADP-ribosylationDisulfide bondIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

AmyloidosisDeafnessDisease variantNon-syndromic deafness

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonEndoplasmic reticulumGolgi apparatusInflammasomeMembraneMitochondrionNucleusSecreted

Biological process

ImmunityInflammatory responseInnate immunityTranscriptionTranscription regulation

Domain

Leucine-rich repeatRepeat

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