Urethane

• Description:

  Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

• Product Name Alternative:

  Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H350

• Target:

  Bacterial; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Urethane.html

• Purity:

  99.99

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  NC(OCC)=O

• Molecular Formula:

  C3H7NO2

• Molecular Weight:

  89.09

• Precautions:

  H302, H350

• References & Citations:

  [1]K J Field, et al. Hazards of urethane (ethyl carbamate) : a review of the literature. Lab Anim. 1988 Jul;22 (3) :255-62.|[2]R E Sotomayor, et al. Mutagenicity, metabolism, and DNA interactions of urethane. Toxicol Ind Health. 1990 Jan;6 (1) :71-108.|[3]Zheng J, et al. Overexpression of PRDX4 Modulates Tumor Microenvironment and Promotes Urethane-Induced Lung Tumorigenesis. Oxid Med Cell Longev. 2020 Dec 28;2020:8262730.|[4]Sozio F, et al. Urethane-induced lung carcinogenesis. Methods Cell Biol. 2021;163:45-57. |[5]Gurley KE, et al. Induction of Lung Tumors in Mice with Urethane. Cold Spring Harb Protoc. 2015 Sep 1;2015 (9) :pdb.prot077446.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 4

• CAS Number:

  [51-79-6]