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NEK2 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334480-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334480-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protein kinase that is involved in mitotic regulation. Integral component of the mitotic spindle-assembly checkpoint which is necessary for proper chromosome segregation during metaphase-anaphase transition. Required for association of MAD2L1 to kinetochore.
Product Name Alternative
HsPK21; NEK2; NEK2A; NLK1
UniProt
P51955
Reactivity
Human
Immunogen
A synthesized peptide derived from human NEK2
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P51955

Serine/threonine-protein kinase Nek2

NEK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51955
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NEK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
Q53FD6, Q5I1Z9, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Biological process

Cell cycleCell divisionChromosome partitionMeiosisMitosis

Cellular component

CentromereChromosomeCytoplasmCytoskeletonKinetochoreMicrotubuleNucleus

Domain

Coiled coil

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Disease

Retinitis pigmentosa

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