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Ciprofibrate

CAT: 0804-HY-B0664-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0664-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ciprofibrate (Win35833) is a potent peroxisome proliferator and increases the phosphorylation level of the PPARalpha[1]. Ciprofibrate acts as an orally active hypolipidaemic agent and can be used for the research of primary hyperlipidaemias[2].
CAS Number
52214-84-3
Product Name Alternative
Win35833
UNSPSC
12352005
Hazard Statement
H350
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Ciprofibrate.html
Concentration
10mM
Purity
99.93
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(C)(OC1=CC=C(C2C(Cl)(Cl)C2)C=C1)C(O)=O
Molecular Formula
C13H14Cl2O3
Molecular Weight
289.15
Precautions
H350
References & Citations
[1]Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate. Biochem Pharmacol, 1999. 58 (6) : p. 1001-8.|[2]Agnes M Rimando, et al. Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters. J Agric Food Chem. 2005 May 4;53 (9) :3403-7.|[3]Thing-Fong Tzeng, et al. 6-gingerol protects against nutritional steatohepatitis by regulating key genes related to inflammation and lipid metabolism. Nutrients. 2015 Feb 4;7 (2) :999-1020.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
PPARα

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