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LRRK2 Antibody (C-term)

CAT: 0013-GTR18325468-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18325468-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin, LRRK2, PARK8
UniProt
Q5S007
Reactivity
Human
Immunogen
This LRRK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2171-2207 amino acids from the C-terminal region of human LRRK2.
Target
LRRK2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Dilution
WB - 1:1000, IHC - 1:25, FC - 1:25
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
286103 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
FC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q5S007

Leucine-rich repeat serine/threonine-protein kinase 2

LRRK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5S007
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LRRK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1, 3.6.5.-
Processing
—
Secondary accessions
A6NJU2, Q6ZS50, Q8NCX9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

ATP-bindingGTP-bindingNucleotide-binding

Biological process

AutophagyDifferentiation

Cellular component

Cell projectionCytoplasmCytoplasmic vesicleCytoskeletonEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembraneMitochondrionMitochondrion outer membraneSynapse

Domain

Coiled coilLeucine-rich repeatRepeatWD repeat

Disease

Disease variantNeurodegenerationParkinson diseaseParkinsonism

Molecular function

GTPase activationHydrolaseKinaseSerine/threonine-protein kinaseTransferase

PTM

PhosphoproteinUbl conjugation

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