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VU0542270

CAT: 0804-HY-162322-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162322-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU0542270 is a selective vascular Kir6.1/SUR2B KATP channel inhibitor with an IC50 value of 100 nM. VU0542270 has an IC50 > 30 μM for the other nine members of the Kir channel family. VU0542270 can be used in the study of cardiovascular disease[1].
CAS Number
1396814-79-1
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vu0542270.html
Purity
98.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(CNC(NC2=CC=CS2)=O)SC(C3=CC=CS3)=N1
Molecular Formula
C14H13N3OS3
Molecular Weight
335.47
References & Citations
[1]Li K, et al. Discovery and Characterization of VU0542270, the First Selective Inhibitor of Vascular Kir6.1/SUR2B KATP Channels. Mol Pharmacol. 2024 Feb 15;105 (3) :202-212.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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GTR19234846-01VU0542270

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