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BACE1 Rabbit mAb

CAT: 0013-GTR18321387-02Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18321387-02Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BACE1 Rabbit mAb
Product Name Alternative
BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
UniProt
P56817
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human BACE1
Clonality
Monoclonal
Clone
BT27X3F8
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity Chromatography
Dilution
WB: 1/500-1/1000 IP: 1/40
Form
Liquid
Molecular Weight
Calculated MW: 56 kDa; Observed MW: 68 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IP, WB
Preservative
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% rAlbumin, 0.02% sodium azide and 50% glycerol.
Isotype
IgG

UniProtKB · P56817

Beta-secretase 1

BACE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BACE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.23.46
Processing
Precursor
Secondary accessions
A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5, Q9ULS1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugationZymogen

Coding sequence diversity

Alternative splicing

Molecular function

Aspartyl proteaseHydrolaseProtease

Cellular component

Cell membraneCell projectionCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembrane

Domain

SignalTransmembraneTransmembrane helix

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