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Ziptide

CAT: 0804-HY-P10367Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10367Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ziptide is a substrate for MAPK activated protein kinase 2 (MAPKAPK2, Km = 5 μM), MAPKAPK3 (Km = 30 μM), PARK (Km = 40 μM), checkpoint kinase 1 (Chk1, Km = 5 μM), AMP-activated protein kinase (AMPK, Km = 75 μM), and calcium/calmodulin-dependent protein kinase II (CamKII, Km = 300 μM) [1].
CAS Number
518069-98-2
UNSPSC
12352209
Target
AMPK; Checkpoint Kinase (Chk) ; MAPKAPK2 (MK2)
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; MAPK/ERK Pathway; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ziptide.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N2[C@@H](CCC2)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N
Molecular Formula
C65H109N19O19
Molecular Weight
1460.68
References & Citations
[1]Ross, H., et al. A non-radioactive method for the assay of many serine/threonine-specific protein kinases. Biochem J. 366 (Pt 3), 977-981 (2002) .
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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