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Simethicone

CAT: 0804-HY-109519-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-109519-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Simethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic[1].
CAS Number
8050-81-5
UNSPSC
12352211
Hazard Statement
H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/simethicone.html
Purity
95.6
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[Simethicone]
Precautions
H319, H335
References & Citations
[1]Voepel-Lewis TD, et al. Evaluation of simethicone for the treatment of postoperative abdominal discomfort in infants. J Clin Anesth. 1998 Mar;10 (2) :91-4. |[2]Bueno L, et al. Influence of simethicone and alverine on stress-induced alterations of colonic permeability and sensitivity in rats: beneficial effect of their association. J Pharm Pharmacol. 2013 Apr;65 (4) :567-73. |[3]da Silva KG, et al. Influence of simethicone and fasting on the quality of abdominal ultrasonography in New Zealand White rabbits. Acta Vet Scand. 2017 Jul 17;59 (1) :48.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched

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