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Heptaminol

CAT: 0804-HY-W685943-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W685943-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Heptaminol is a fatty amine with pressor properties and a potential antihypotension agent. Heptaminol is also a competitive inhibitor of norepinephrine uptake and an inhibitor of nicotine-induced catecholamine release (IC50: 650 μM) . Heptaminol does not inhibit norepinephrine release induced by 59 mM K+ but rather inhibits high-affinity Na+-dependent norepinephrine uptake[1][2].
CAS Number
372-66-7
UNSPSC
12352211
Hazard Statement
H302, H315, H318, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/heptaminol.html
Purity
98.0
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC(C)(CCCC(C)N)C
Molecular Formula
C8H19NO
Molecular Weight
145.25
Precautions
H302, H315, H318, H335
References & Citations
[1]Dib J, et al. Is heptaminol a (major) metabolite of octodrine? Drug Test Anal. 2019 Nov;11 (11-12) :1761-1763.|[2]Delicado EG, et al. Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. Biochem Pharmacol. 1990 Aug 15;40 (4) :821-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3

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