MLCK inhibitor peptide 18

• UNSPSC Description:

  MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.

• Target Antigen:

  Autophagy; CaMK; Myosin

• Type:

  Reference compound

• Related Pathways:

  Autophagy;Cytoskeleton;Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/MLCK_inhibitor_peptide_18.html

• Purity:

  99.94

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  [K][R]([Y]([Y][R][R](N)[K])[K])[K]

• Molecular Weight:

  1324.62

• References & Citations:

  [1]Lukas TJ, et al. Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge. J Med Chem. 1999 Mar 11;42(5):910-9.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  224579-74-2