Anastrozole

Anastrozole

• CAS Number: 120511-73-1
• UNSPSC Description: Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM.
• Target Antigen: Cytochrome P450
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/Anastrozole.html
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: CC(C)(C#N)C1=CC(C(C)(C#N)C)=CC(CN2C=NC=N2)=C1
• Molecular Weight: 293.37
• References & Citations: [1]Dukes M, et al. The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor. J Steroid Biochem Mol Biol. 1996 Jul;58(4):439-45.
• Shipping Conditions: Room Temperature
• Clinical Information: Launched