KRAS G12D inhibitor 24
CAT:
804-HY-158703
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
KRAS G12D inhibitor 24
- CAS Number: 3033701-29-7
- UNSPSC Description: KRAS G12D inhibitor 24 (compound 103) is a potent inhibitor of KRAS G12D, with the IC50 of 0.004 μM. KRAS G12D inhibitor 24 has oral bioactivity[1].
- Target Antigen: Ras
- Type: Reference compound
- Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/kras-g12d-inhibitor-24.html
- Smiles: OC1=CC(C2=C(F)C3=NC(OC[C@]4(C)CN(C)CC/C4=C\F)=NC(N5C[C@H](N6)CC[C@H]6C5)=C3C=N2)=C7C(C#C)=C(F)C=CC7=C1
- Molecular Weight: 614.66
- References & Citations: [1]Tyligand Bioscience (Shanghai) Limited. Quinazoline compounds as KRAS inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cancer. World Intellectual Property Organization, WO2024067714 A1 2024-04-04
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported