m3227G(5)ppp(5')m6Am (triammonium)

m3227G(5)ppp(5')m6Am (triammonium)

• UNSPSC Description: m3227G(5)ppp(5')m6Am triammonium is the triammonium salt form of m3227G(5)ppp(5')m6Am (HY-164986). m3227G(5)ppp(5')m6Am triammonium is a specific mRNA molecule structure, which is composed of a 3227-methylguanine (m3227G) cap, a triphosphate group and a N6,2'-O-dimethyladenosine. m6Am is a reversible modification located on the first coding nucleotide near the 5' cap of mRNA, that can affect the stability of mRNA[1].
• Target Antigen: DNA/RNA Synthesis
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/m3227g-5-ppp-5-m6am-triammonium.html
• Smiles: O=C1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(OC[C@H]4O[C@@H](N(C=N5)C6=C5C(NC)=NC=N6)[C@H](OC)[C@@H]4O)(O)=O)(O)=O)([O-])=O)O3)C=[N+]2C)NC(N(C)C)=N1.N.N.N
• Molecular Weight: 893.63
• References & Citations: [1]Mauer J, et al., Reversible methylation of m6Am in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541(7637):371-375.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported