Products for Research Use Only
RegisterLogin

PAX6 Antibody

CAT: 0013-GTR18317561Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18317561Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
UniProt
P26367
Reactivity
Human
Immunogen
A recombinant partial protein (within amino acids 1-300) from the human protein was used as the immunogen for the PAX6 antibody.
Clonality
Recombinant
Clone
PAX6/8578R
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the PAX6 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG, kappa

Related Products

CatalogName
GTR18047400-01PAX6 polyclonal antibody
GTR18291490-01PAX6 monoclonal antibody
GTR17697291PAX6 (internal) Antibody
GTR18299921-01PAX6 monoclonal antibody
GTR18327149-01PAX6-T373 Antibody
GTR18272548PAX6 Conjugated Antibody
GTR18298884-01PAX6 monoclonal antibody
GTR18895585PAX6 peptide
GTR18914398PAX6 Peptide
GTR19060551PAX6 Peptide

Alternative Products

CatalogName
33-452PAX6 Antibody [PAX6/1166]
33-183PAX6 Antibody [PAX6/498]
20R-1682PAX6 antibody

Popular Products