Products for Research Use Only
RegisterLogin

Recombinant CD3 epsilon Antibody

CAT: 0013-GTR18318079Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18318079Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR) . Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
UniProt
P07766
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the recombinant CD3 epsilon antibody.
Clonality
Recombinant
Clone
C3e/8115R
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant CD3 epsilon antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG, kappa

UniProtKB · P07766

T-cell surface glycoprotein CD3 epsilon chain

CD3E_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P07766
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD3E
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K997
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Cellular component

Cell membraneMembrane

PTM

Disulfide bondPhosphoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

Molecular function

Receptor

Related Products

CatalogName
GTR18571314-01Recombinant CD3e Antibody / CD3 epsilon
GTR18571313Recombinant CD3e Antibody / CD3 epsilon
GTR18318013CD3 epsilon Antibody
GTR18082058-01CD3 epsilon Antibody
GTR18075066-01CD3 epsilon Antibody
GTR18074890-01CD3 epsilon Antibody
GTR18573697CD3 epsilon Antibody
GTR18571782CD3 epsilon Antibody
GTR18303705CD3 epsilon Antibody
GTR18089902-01CD3 epsilon Antibody

Alternative Products

CatalogName
V4205SAF-100UGRecombinant CD3 epsilon Antibody
RC-15772-01Recombinant IKK epsilon Antibody
bsm-52386R-TRCD3 epsilon Recombinant Antibody
bsm-62955R-01PKC epsilon Recombinant Antibody
bsm-54094R-01IKB epsilon Recombinant Antibody
bsm-61011R-TREIF2B epsilon Recombinant Antibody
bsm-61720R-TRIKK epsilon Recombinant Antibody
RC-15625-01Recombinant PKC epsilon Antibody
V9459SAF-100UGRecombinant CD3e Antibody / CD3 epsilon
AN300740L-01Recombinant IKB epsilon Monoclonal Antibody

Popular Products