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CCL18 Antibody / PARC

CAT: 0013-GTR18317344Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18317344Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chemokines are members of a superfamily of small inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP) -1a, MIP-1b, MIP-2, MIP-3a, MIP-3b, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. MIP-4 is constituitively expressed in several normal tissues and is highly expressed in plasma.
UniProt
P55774
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 1-89) from the human protein was used as the immunogen for the CCL18 antibody.
Clonality
Monoclonal
Clone
CCL18/3744
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CCL18 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG

UniProtKB · P55774

C-C motif chemokine 18

CCL18_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P55774
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCL18
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B5BUM2, Q53X71
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

ChemotaxisInflammatory response

Molecular function

Cytokine

PTM

Disulfide bond

Cellular component

Secreted

Domain

Signal

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