Products for Research Use Only

SLC2A1 Antibody / GLUT-1

CAT: 0013-GTR18317139-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18317139-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative) .
UniProt
P11166
Reactivity
Human
Immunogen
A recombinant fragment of human GLUT1 protein (within amino acids 200-400) was used as the immunogen for the SLC2A1 antibody.
Clonality
Monoclonal
Clone
GLUT1/7308
Conjugation
Unconjugated
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the SLC2A1 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Mouse IgG

UniProtKB · P11166

Solute carrier family 2, facilitated glucose transporter member 1

GTR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11166
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC2A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K9S6, B2R620, D3DPX0, O75535, Q0P512, Q147X2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinPhosphoprotein

Disease

CataractDisease variantDystoniaEpilepsyHereditary hemolytic anemiaIntellectual disability

Cellular component

Cell membraneMembrane

Biological process

Sugar transportTransport

Domain

TransmembraneTransmembrane helix