Products for Research Use Only
RegisterLogin

PAX8 Antibody

CAT: 0013-GTR18316930-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18316930-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
UniProt
Q06710
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 150-300) from the human protein was used as the immunogen for the PAX8 antibody.
Clonality
Recombinant
Clone
PAX8/8651R
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the PAX8 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG, kappa

Related Products

CatalogName
GTR18212546Mouse PAX8, clone PAX8/1492 (Monoclonal) Antibody
GTR18290505-01PAX8 monoclonal antibody
GTR18273512PAX8 Conjugated Antibody
GTR18281342PAX8 Conjugated Antibody
GTR18047786-01PAX8 polyclonal antibody
GTR18046387-01PAX8 polyclonal antibody
GTR19055009PAX8 Peptide
GTR18914397PAX8 Peptide
GTR18899523-01PAX8 peptide
GTR18914396PAX8 Peptide

Alternative Products

CatalogName
33-765PAX8 Antibody [PAX8/1491]
33-766PAX8 Antibody [PAX8/1492]
NBP3-07355-100ugMouse Monoclonal PAX8 Antibody (PAX8/1491 + PAX8/1492)
70R-19129PAX8 antibody
NBP3-08274PCPMouse Monoclonal PAX8 Antibody (PAX8/1491 + PAX8/1492) [PerCP]

Popular Products