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S100P Antibody / MIG9

CAT: 0013-GTR18316773-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18316773-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D. S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
UniProt
P25815
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 1-95) from the human protein was used as the immunogen for the S100P antibody.
Clonality
Recombinant
Clone
S100P/7978R
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the S100P antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG, kappa

UniProtKB · P25815

Protein S100-P

S100P_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P25815
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
S100P
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5J7W2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumMetal-binding

Cellular component

Cell membraneCell projectionCytoplasmMembraneNucleus

Domain

Repeat

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