Products for Research Use Only

Interleukin-2 Antibody / IL-2

CAT: 0013-GTR18316762Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18316762Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-2 (IL-2) is a T cell stimulatory cytokine that induces T cell proliferation and NK cell proliferation and activation. Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7) . IL-2 induces CTLA-4 and also functions as a survival factor for lymphocytes.
UniProt
P60568
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 21-153) from the human protein was used as the immunogen for the Interleukin-2 antibody.
Clonality
Monoclonal
Clone
IL2/4987
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Interleukin-2 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2b, kappa

UniProtKB · P60568

Interleukin-2

IL2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P60568
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-2
EC number
—
Processing
Precursor
Secondary accessions
P01585
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Chromosomal rearrangement

Molecular function

CytokineGrowth factor

PTM

Disulfide bondGlycoprotein

Disease

Proto-oncogene

Cellular component

Secreted

Domain

Signal