AF/LE Purified Anti-Mouse CD132 Antibody

• Background:

  CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID) .

• Synonyms:

  Cytokine receptor common subunit gamma, Il2rg, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132

• Gene ID:

  16186

• Swiss Prot:

  P34902

• Host:

  Rat

• Reactivity:

  Mouse

• Isotype:

  IgG2b κ

• Conjugation:

  None (Purified antibody-Azide Free/Low endotoxin)

• Applications:

  FCM

• Concentration:

  0.5 mg/mL

• Buffer:

  0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

• Storage Conditions:

  Store at 2~8°C. Do not freeze.

• CAS Number:

  9007-83-4