FITC Anti-Human CD11b Antibody

• Background:

  CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

• Synonyms:

  Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b

• Gene ID:

  3684

• Swiss Prot:

  P11215

• Host:

  Mouse

• Reactivity:

  Human

• Isotype:

  IgG1 κ

• Conjugation:

  FITC

• Applications:

  FCM

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• CAS Number:

  9007-83-4