AF647 Anti-Mouse CD3 Antibody

• Background:

  CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

• Synonyms:

  T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain, CD3E/D/G/Z, CD3e/d/g/z, CD3E/D/G/Z, CD3

• Gene ID:

  12502

• Swiss Prot:

  P04235, P11942, P22646, P24161

• Host:

  Rat

• Reactivity:

  Mouse

• Isotype:

  IgG2b κ

• Conjugation:

  AF647

• Applications:

  FCM

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• CAS Number:

  9007-83-4