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DSG2 antibody

CAT: 0710-FNab10768Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10768Size:100 µg
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Background
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Synonyms
Desmoglein-2|Cadherin family member 5|HDGC|DSG2|CDHF5
Gene ID
1829
UniProt
Q14126
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Desmoglein 2
Target
DSG2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
150 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
846-1118aa

UniProtKB · Q14126

Desmoglein-2

DSG2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14126
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DSG2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q4KKU6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

CalciumMetal-binding

Disease

CardiomyopathyDisease variant

Biological process

Cell adhesion

Cellular component

Cell junctionCell membraneCytoplasmMembraneSecreted

PTM

Cleavage on pair of basic residuesGlycoproteinLipoproteinPalmitatePhosphoprotein

Domain

RepeatSignalTransmembraneTransmembrane helix

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