Sildenafil-d3-1

Sildenafil-d3-1

• CAS Number: 1126745-87-6
• UNSPSC Description: Sildenafil-d3-1 (UK-92480-d3-1) is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
• Target Antigen: Phosphodiesterase (PDE)
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Solubility: 10 mM in DMSO
• Smiles: CN1CCN(S(C2=C([2H])C([2H])=C(OCC)C(C3=NC(C(CCC)=NN4C)=C4C(N3)=O)=C2[2H])(=O)=O)CC1
• Molecular Weight: 477.59
• References & Citations: [1]Wang Z, et al. The Selectivity and Potency of the New PDE5 Inhibitor TPN729MA. J Sex Med. 2013 Nov;10(11):2790-7
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported