Datopotamab
CAT:
804-HY-P99843-01
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Datopotamab
- CAS Number: 2267989-53-5
- UNSPSC Description: Datopotamab (CDP7657) is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer[1].
- Target Antigen: ADC Antibody; TROP2
- Type: Inhibitory Antibodies
- Related Pathways: Antibody-drug Conjugate/ADC Related;Immunology/Inflammation
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/datopotamab.html
- Purity: 99.00
- Solubility: 10 mM in DMSO
- Smiles: [Datopotamab]
- References & Citations: [1]Okajima D, et al. Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells. Mol Cancer Ther. 2021 Dec;20(12):2329-2340.
- Shipping Conditions: Dry Ice
- Storage Conditions: Store at -80°C for 2 years
- Clinical Information: Phase 3