Tagtociclib (hydrate)
CAT:
804-HY-137894A-06
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tagtociclib (hydrate)
- CAS Number: 2733575-91-0
- UNSPSC Description: PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).
- Target Antigen: CDK; GSK-3
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR;Stem Cell/Wnt
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pf-07104091-hydrate.html
- Smiles: O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2.[H]O[H]
- Molecular Weight: 422.48
- References & Citations: [1]Douglas Carl BEHENNA, et al. Cdk2 inhibitors. WO2020157652A2.
- Shipping Conditions: Room Temperature