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BX430

CAT: 0804-HY-110237-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-110237-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BX430 is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. BX430 has species specificity. BX430 is used for chronic pain and cardiovascular disease.
CAS Number
688309-70-8
UNSPSC
12352005
Hazard Statement
H302
Target
Calcium Channel; P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bx430.html
Purity
99.21
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=CN=C1)NC2=C(Br)C=C(C(C)C)C=C2Br
Molecular Formula
C15H15Br2N3O
Molecular Weight
413.11
Precautions
H302
References & Citations
[1]Ase AR, et al. Identification and characterization of a selective allosteric antagonist of human P2X4 receptor channels. Mol Pharmacol. 2015 Apr;87 (4) :606-16. |[2]Sophocleous RA, et al. Pharmacological and genetic characterisation of the canine P2X4 receptor. Br J Pharmacol. 2020 Feb 4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2X4 Receptor

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CatalogName
BA6575-50BX430

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