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NOTCH1 Reference Antibody

CAT: 0013-GTR18311365-02Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18311365-02Size:1 mg
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Description
Anti-NOTCH1 Reference Antibody (Pfizer patent anti-Notch1)
UniProt
P46531
Reactivity
Human
Target
NOTCH1
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research
Purification
Protein A
Concentration
Batch dependent
Purity
>95%
Molecular Weight
150 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, FA, FACS, In vivo
Preservative
100 mM Proline/Acetic acid 20mM Arginine pH 5.0

UniProtKB · P46531

Neurogenic locus notch homolog protein 1

NOTC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 1, hN1
EC number
—
Processing
Precursor
Secondary accessions
Q59ED8, Q5SXM3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Biological process

AngiogenesisDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

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