Products for Research Use Only

Nectin-4 Antibody (MMAE)

CAT: 0013-GTR18311089-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18311089-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-Nectin-4 Reference Antibodyd antibody and Monomethyl auristatin E (MMAE), suitable for adult patients with locally advanced or metastatic urothelial carcinoma, or who have received programmed cell death protein 1 (PD-1) inhibitor or programmed cell death ligand 1 (PD-L1) inhibitor therapy or neoadjuvant/adjuvant platinum-based chemotherapy for locally advanced or metastatic cancer.
UniProt
Q96NY8
Reactivity
Human
Target
Nectin-4
Clonality
Recombinant
Conjugation
MMAE
Field of Research
Cancer Biology
Purification
Protein A
Concentration
Batch dependent
Purity
>95%
Molecular Weight
143.9 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, FA, FACS, In vivo
Preservative
100 mM Proline/Acetic acid 20mM Arginine pH 5.0

UniProtKB · Q96NY8

Nectin-4

NECT4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96NY8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NECTIN4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DQW3, Q96K15
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionHost-virus interaction

Cellular component

Cell junctionCell membraneMembraneSecreted

Disease

Disease variantEctodermal dysplasia

PTM

Disulfide bondGlycoprotein

Molecular function

Host cell receptor for virus entryReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix