Cefditoren

• Description:

  Cefditoren is an orally active antibiotic with broad-spectrum antibacterial activity, capable of inhibiting both Gram-negative and Gram-positive bacteria. It has a MIC50 of 0.25-0.5 mg/L against Streptococcus pneumoniae strains. Cefditoren is effective against respiratory tract infections and skin infections[1][2][3].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cefditoren.html

• Purity:

  98.14

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  OC(C1=C(/C=C\C2=C(N=CS2)C)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC)=O)([H])N1C3=O)=O

• Molecular Formula:

  C19H18N6O5S3

• Molecular Weight:

  506.58

• References & Citations:

  [1]Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD) : National Institute of Child Health and Human Development; 2006–. Cefditoren. 2023 Aug 15.|[2]Giuliano S, et al. Cefditoren: a clinical overview. New Microbiol. 2023 Feb;46 (1) :9-17.|[3]Sempere J, et al. A national longitudinal study evaluating the activity of cefditoren and other antibiotics against non-susceptible Streptococcus pneumoniae strains during the period 2004-20 in Spain. J Antimicrob Chemother. 2022 Mar 31;77 (4) :1045-1051.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 4

• CAS Number:

  [104145-95-1]